DNA Binding Motif

Accessions: MA1146.1 (JASPAR 2024)
Names: NR1A4::RXRA, NR1H4::RXRA
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: SMiLE-seq
Length: 15
Consensus: grGkTCAtTGACCyy
Weblogo:
PSSM: P0 A C G T
01 223 172 451 154 g
02 653 55 280 11 r
03 29 15 937 19 G
04 22 9 646 324 k
05 24 49 101 826 T
06 11 875 13 100 C
07 720 13 249 17 A
08 144 121 75 660 t
09 23 92 48 838 T
10 108 102 753 37 G
11 763 112 78 48 A
12 134 773 9 83 C
13 113 798 38 51 C
14 25 383 71 521 y
15 95 313 212 380 y
Type: Heterodimer
Binding TFs: Q96RI1 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
P19793 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains), Nuclear/hormone receptor activator site AF-1)
P19793
Q96RI1
Publications: Laffitte B. A., Kast H. R., Nguyen C. M., Zavacki A. M., Moore D. D., Edwards P. A. Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor.. J. Biol. Chem. 275:10638-10647 (2000). [Pubmed]

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