DNA Binding Motif

Accessions: 4r2q_A (3D-footprint 20231221)
Names: Wilms tumor protein, isoform 4/CRA_a
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Wilms Tumor Protein (WT1) zinc fingers in complex with formylated DNA
Length: 9
Consensus: aGCCCACGC
Weblogo:
PSSM: P0 A C G T
01 45 16 16 19 a
02 10 10 66 10 G
03 0 96 0 0 C
04 2 90 2 2 C
05 3 85 3 5 C
06 96 0 0 0 A
07 8 72 8 8 C
08 0 0 96 0 G
09 9 67 9 11 C
Binding TFs: 4r2q_A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 4r2q_B
4r2q_C
Publications: Hashimoto H, Olanrewaju Y.O, Zheng Y, Wilson G.G, Zhang X, Cheng X. Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes & development 28:2304-13 (2014). [Pubmed]

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