DNA Binding Motif

						

			
Accessions: SRF_full (HumanTF 1.0), MA0083.3 (JASPAR 2024)

			
Names: SRF
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 16
Consensus: TgmCCATATAWGGkcA
Weblogo: 
PSSM: P0      A      C      G      T
01    214    125     80   1129      T
02     75    152   1144    372      g
03    627    611    144    167      m
04      0   1771     15      0      C
05      3   1787     11     19      C
06   1137     13     18     61      A
07     54      0      6   1571      T
08   1163      0      2      0      A
09      1      5      8   1610      T
10   1162      0      0     16      A
11    439     12      0   1074      W
12      8      9   1896      0      G
13      8      2   1872      7      G
14    262    105    670    686      k
15    337   1023    145     72      c
16    913     63     98    248      A
Type: Heterodimer
Binding TFs: P11831 (SRF-type transcription factor (DNA-binding and dimerisation domain))
SRF_full (SRF-type transcription factor (DNA-binding and dimerisation domain))
P11831
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Pollock R., Treisman R. A sensitive method for the determination of protein-DNA binding specificities. Nucleic Acids Res. 18:6197-6204 (1990). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.