DNA Binding Motif

						

			
Accessions: 1lb2_ABE (3D-footprint 20231221)

			
Names: CATABOLITE GENE ACTIVATOR PROTEIN
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the E. coli alpha C-terminal domain of RNA polymerase in complex with CAP and DNA
Length: 17
Consensus: TwnnnnnnnnnntGtGA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02     24      8      8     56      w
03     24     24     24     24      n
04     24     24     24     24      n
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13      8     16      8     64      t
14      0      0     96      0      G
15      8      8     16     64      t
16      0      0     96      0      G
17     96      0      0      0      A
Binding TFs: 1lb2_A (Cyclic nucleotide-binding domain, Bacterial regulatory proteins, crp family, Crp-like helix-turn-helix domain)
Binding Sites: 1lb2_J
1lb2_K
			
Publications: Benoff B., Yang H., Lawson CL., Parkinson G., Liu J., Blatter E., Ebright YW., Berman HM., Ebright RH. Structural basis of transcription activation: the CAP-alpha CTD-DNA complex. Science. 297(5586):1562-6 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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