DNA Binding Motif

						

			
Accessions: PAX3_DBD (HumanTF 1.0), MA0780.1 (JASPAR 2024)

			
Names: PAX3
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 2, HT-SELEX
Length: 10
Consensus: TAATyrATTA
Weblogo: 
PSSM: P0      A      C      G      T
01   1994    243    394   7945      T
02   7945     32     96     31      A
03   7945     24     12     13      A
04      9    101     17   7945      T
05     12   5267     62   2678      y
06   2684     48   5261      7      r
07   7945     22     57     31      A
08      0     14     14   7945      T
09     58     97     42   7945      T
10   7945    233    197   1061      A
Type: Heterodimer
Binding TFs: P23760 (Homeobox domain, 'Paired box' domain, Paired box protein 7 )
PAX3_DBD (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
P23760
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Kumar D., Shadrach J. L., Wagers A. J., Lassar A. B. Id3 is a direct transcriptional target of Pax7 in quiescent satellite cells.. Mol. Biol. Cell 20:3170-3177 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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