DNA Binding Motif

Accessions: 5d39_AC (3D-footprint 20210203)
Names: Signal transducer and activator of transcription 6
Organisms: Homo sapiens
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Transcription factor-DNA complex
Length: 9
Consensus: TTCCnGGAA
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 0 0 0 96 T
03 0 96 0 0 C
04 9 67 9 11 C
05 24 24 24 24 n
06 9 9 69 9 G
07 0 0 96 0 G
08 69 9 9 9 A
09 96 0 0 0 A
Type: Heterodimer
Binding TFs: 5d39_A (STAT protein, all-alpha domain, STAT protein, DNA binding domain, SH2 domain)
5d39_C (STAT protein, all-alpha domain, STAT protein, DNA binding domain, SH2 domain)
Binding Sites: 5d39_N
5d39_M
Publications: Li J, Rodriguez JP, Niu F, Pu M, Wang J, Hung LW, Shao Q, Zhu Y, Ding W, Liu Y, Da Y, Yao Z, Yang J, Zhao Y, Wei GH, Cheng G, Liu ZJ, Ouyang S. Structural basis for DNA recognition by STAT6. Proc Natl Acad Sci U S A 113:13015-13020 (2016). [Pubmed]

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