DNA Binding Motif

						

			
Accessions: MA0144.2 (JASPAR 2024)

			
Names: STAT3
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 11
Consensus: yTKCykGGAAr
Weblogo: 
PSSM: P0      A      C      G      T
01   1936   8571   3801   7312      y
02    708      0      0  20912      T
03    250    346   5850  15174      K
04   1006  19585      0   1029      C
05    840   7780      0  13000      y
06   3692      0  11456   6472      k
07   1574      0  20046      0      G
08   2532      0  18686    402      G
09  21620      0      0      0      A
10  21620      0      0      0      A
11   9311    962   6579   4768      r
Type: Heterodimer
Binding TFs: P40763 (SH2 domain, STAT protein, all-alpha domain, STAT protein, DNA binding domain, STAT protein, protein interaction domain)
P40763
Binding Sites: MA0144.2.1
MA0144.2.10
MA0144.2.11
MA0144.2.12
MA0144.2.13
MA0144.2.14
MA0144.2.15
MA0144.2.16
MA0144.2.17
MA0144.2.18
MA0144.2.19
MA0144.2.2
MA0144.2.20
MA0144.2.3
MA0144.2.4
MA0144.2.5
MA0144.2.6
MA0144.2.7
MA0144.2.8
MA0144.2.9
			
Publications: Chen X, Xu H, Yuan P, Fang F, Huss M, Vega V.B, Wong E, Orlov Y.L, Zhang W, Jiang J, Loh Y.H, Yeo H.C, Yeo Z.X, Narang V, Govindarajan K.R, Leong B, Shahab A, Ruan Y, Bourque G, Sung W.K, Clarke N.D, Wei C.L, Ng H.H. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-17 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.