DNA Binding Motif

						

			
Accessions: UP00108A_1 (UniPROBE 20160601)

			
Names: Alx3, aristaless 3, Homeobox protein aristaless-like 3, Proline-rich transcription factor ALX3
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: wawayTAATTAryTsav
Weblogo: 
PSSM: P0      A      C      G      T
01   0.30   0.03   0.13   0.54      w
02   0.37   0.20   0.24   0.19      a
03   0.41   0.18   0.16   0.25      w
04   0.53   0.15   0.23   0.08      a
05   0.04   0.48   0.01   0.47      y
06      0   0.08      0   0.91      T
07   0.99   0.01      0      0      A
08   0.99      0   0.01      0      A
09      0   0.01      0   0.99      T
10      0      0   0.01   0.99      T
11   0.91      0   0.08      0      A
12   0.47   0.01   0.48   0.04      r
13   0.08   0.44   0.05   0.42      y
14   0.07   0.15   0.10   0.68      T
15   0.24   0.27   0.34   0.15      s
16   0.43   0.19   0.14   0.24      a
17   0.26   0.25   0.29   0.20      v
Binding TFs: UP00108A (Homeobox domain)
Binding Sites: AATAATTA
AATTAATT
ACTAATTA
AGTAATTA
ATAATTAA
ATAATTAG
ATTAATTA
ATTAATTG
CATAATTA
CCTAATTA
CTAATTAA
CTAATTAC
CTTAATTA
GATAATTA
GCTAATTA
GTAATTAA
GTTAATTA
TAATTAAA
TAATTAGA
TTAATTAA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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