DNA Binding Motif

Accessions: MA1368.1 (JASPAR 2024), M0789 (AthalianaCistrome v4_May2016)
Names: AT3G25990, GT-4, AT3G25990.DAP, T11979;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: DAP-seq
Length: 21
Consensus: AACCATGGTTAAawywtaacm
Weblogo:
PSSM: P0 A C G T
01 75 0 3 0 A
02 78 0 0 0 A
03 0 78 0 0 C
04 0 61 0 17 C
05 62 0 16 0 A
06 0 15 2 61 T
07 17 0 61 0 G
08 4 0 74 0 G
09 0 1 0 77 T
10 0 2 0 76 T
11 77 1 0 0 A
12 63 2 13 0 A
13 38 9 16 15 a
14 33 3 6 36 w
15 9 23 5 41 y
16 22 4 8 44 w
17 15 2 10 51 t
18 46 10 7 15 a
19 49 6 7 16 a
20 17 41 7 13 c
21 24 38 4 12 m
Type: Heterodimer
Binding TFs: Q9LU92 / T11979 (Myb/SANT-like DNA-binding domain, Myb/SANT-like DNA-binding domain)
Q9LU92
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

Nagata T, Niyada E, Fujimoto N, Nagasaki Y, Noto K, Miyanoiri Y, Murata J, Hiratsuka K, Katahira M. Solution structures of the trihelix DNA-binding domains of the wild-type and a phosphomimetic mutant of Arabidopsis GT-1: mechanism for an increase in DNA-binding affinity through phosphorylation. Proteins 78:3033-47 (2010). [Pubmed]

O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]

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