DNA Binding Motif

						

			
Accessions: TFAP2A_DBD_1 (HumanTF 1.0), MA0810.1 (JASPAR 2024)

			
Names: TFAP2A, TFAP2A(var.2)
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 12
Consensus: ysCCCyvrGGCa
Weblogo: 
PSSM: P0      A      C      G      T
01    678   1183    173   1971      y
02    838   1906   4006    147      s
03     15   4006    229      0      C
04      0   4006     10     33      C
05     10   2812    221    963      C
06    197   1653    831   1324      y
07   1324   1439   1054    189      v
08   1697    407   1873     28      r
09    191     34   4006      0      G
10      5    788   4006     10      G
11    101   4006    468    226      C
12   1922    434    979    671      a
Type: Heterodimer
Binding TFs: P05549 (Transcription factor AP-2)
TFAP2A_DBD (Transcription factor AP-2)
P05549
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Eckert D, Buhl S, Weber S, Jäger R, Schorle H. The AP-2 family of transcription factors. Genome Biol : (2005;6(13):246.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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