DNA Binding Motif

Accessions: 6g1l_A (3D-footprint 20231221)
Names: Microphthalmia-associated transcription factor
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: MITF/CLEARbox structure
Length: 5
Consensus: CgTGa
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 16 13 54 13 g
03 0 0 0 96 T
04 0 0 96 0 G
05 54 13 16 13 a
Binding TFs: 6g1l_A (Helix-loop-helix DNA-binding domain)
Binding Sites: 6g1l_B
Publications: Möller K, Sigurbjornsdottir S, Arnthorsson AO, Pogenberg V, Dilshat R, Fock V, Brynjolfsdottir SH, Bindesboll C, Bessadottir M, Ogmundsdottir HM, Simonsen A, Larue L, Wilmanns M, Thorsson V, Steingrimsson E, Ogmundsdottir MH. MITF has a central role in regulating starvation-induced autophagy in melanoma. Sci Rep 9:1055 (2019). [Pubmed]

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