DNA Binding Motif

						

			
Accessions: ESRRB_DBD (HumanTF 1.0), MA0141.3 (JASPAR 2024)

			
Names: ESRRB
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 11
Consensus: TCAAGGTCAww
Weblogo: 
PSSM: P0      A      C      G      T
01    108    373     75   1746      T
02      9   1746    255      7      C
03   1746      1      0      4      A
04   1746      1      3      0      A
05      3      2   1746      1      G
06      1      4   1746      3      G
07      6     11      8   1746      T
08      2   1746      1     15      C
09   1746      0     56      3      A
10    702    256     42   1045      w
11    692    328    189    537      w
Type: Heterodimer
Binding TFs: ESRRB_DBD (Zinc finger, C4 type (two domains))
O95718 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
O95718
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Chen X, Xu H, Yuan P, Fang F, Huss M, Vega V.B, Wong E, Orlov Y.L, Zhang W, Jiang J, Loh Y.H, Yeo H.C, Yeo Z.X, Narang V, Govindarajan K.R, Leong B, Shahab A, Ruan Y, Bourque G, Sung W.K, Clarke N.D, Wei C.L, Ng H.H. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-17 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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