DNA Binding Motif

Accessions: 6dfy_C (3D-footprint 20231221)
Names: Double homeobox protein 4
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Remodeled crystal structure of DNA-bound DUX4-HD2
Length: 6
Consensus: AGAnAA
Weblogo:
PSSM: P0 A C G T
01 67 9 9 11 A
02 0 0 96 0 G
03 96 0 0 0 A
04 24 24 24 24 n
05 67 9 9 11 A
06 67 11 9 9 A
Binding TFs: 6dfy_C (Homeobox domain, Homeobox KN domain)
Binding Sites: 6dfy_E
6dfy_F
Publications: Aihara H, Shi K, Lee JK, Bosnakovski D, Kyba M. Comment on structural basis of DUX4/IGH-driven transactivation. Leukemia 32:2090-2092 (2018). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.