DNA Binding Motif

						

			
Accessions: ComA (DBTBS 1.0)

			
Names: ComA
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 15
Consensus: TGCGKGmygCCGmAA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0      1      T
02      0      0      1      0      G
03      0      1      0      0      C
04      0      0      1      0      G
05      0      0   0.72   0.28      K
06      0      0   0.88   0.12      G
07   0.54   0.31      0   0.15      m
08   0.15   0.31      0   0.54      y
09   0.11   0.23   0.66      0      g
10      0      1      0      0      C
11      0      1      0      0      C
12      0      0      1      0      G
13   0.46   0.54      0      0      m
14      1      0      0      0      A
15      1      0      0      0      A
Binding TFs: ComA (Response regulator receiver domain, Bacterial regulatory proteins, luxR family)
Binding Sites: degQ_1
pel_1
rapA_1
rapC_1
srfAA_2
srfAA_3
			
Publications: Msadek T, Kunst F, Klier A, Rapoport G. DegS-DegU and ComP-ComA modulator-effector pairs control expression of the Bacillus subtilis pleiotropic regulatory gene degQ. Journal of bacteriology 173:2366-77 (1991). [Pubmed]


Mueller J.P, Bukusoglu G, Sonenshein A.L. Transcriptional regulation of Bacillus subtilis glucose starvation-inducible genes: control of gsiA by the ComP-ComA signal transduction system. Journal of bacteriology 174:4361-73 (1992). [Pubmed]


Comella N, Grossman A.D. Conservation of genes and processes controlled by the quorum response in bacteria: characterization of genes controlled by the quorum-sensing transcription factor ComA in Bacillus subtilis. Molecular microbiology 57:1159-74 (2005). [Pubmed]


Lazazzera B.A, Kurtser I.G, McQuade R.S, Grossman A.D. An autoregulatory circuit affecting peptide signaling in Bacillus subtilis. Journal of bacteriology 181:5193-200 (1999). [Pubmed]


Bongiorni C, Ishikawa S, Stephenson S, Ogasawara N, Perego M. Synergistic regulation of competence development in Bacillus subtilis by two Rap-Phr systems. Journal of bacteriology 187:4353-61 (2005). [Pubmed]


Hahn J, Dubnau D. Growth stage signal transduction and the requirements for srfA induction in development of competence. Journal of bacteriology 173:7275-82 (1991). [Pubmed]


Nakano M.M, Xia L.A, Zuber P. Transcription initiation region of the srfA operon, which is controlled by the comP-comA signal transduction system in Bacillus subtilis. Journal of bacteriology 173:5487-93 (1991). [Pubmed]


Roggiani M, Dubnau D. ComA, a phosphorylated response regulator protein of Bacillus subtilis, binds to the promoter region of srfA. Journal of bacteriology 175:3182-7 (1993). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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