DNA Binding Motif

Accessions: 3v79_C (3D-footprint 20231221)
Names: Recombining binding protein suppressor of hairless
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of human Notch1 transcription complex including CSL, RAM, ANK, and MAML-1 on HES-1 promoter DNA sequence
Length: 8
Consensus: TGTGGGAA
Weblogo:
PSSM: P0 A C G T
01 5 5 6 80 T
02 6 5 80 5 G
03 0 0 0 96 T
04 5 5 80 6 G
05 6 5 80 5 G
06 5 5 81 5 G
07 96 0 0 0 A
08 80 5 5 6 A
Binding TFs: 3v79_C (IPT/TIG domain, Beta-trefoil DNA-binding domain, LAG1, DNA binding)
Binding Sites: 3v79_X
3v79_Y
Publications: Choi S.H, Wales T.E, Nam Y, O'Donovan D.J, Sliz P, Engen J.R, Blacklow S.C. Conformational locking upon cooperative assembly of notch transcription complexes. Structure (London, England : 1993) 20:340-9 (2012). [Pubmed]

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