DNA Binding Motif

Accessions: 1hf0_AB (3D-footprint 20231221)
Names: OCTAMER-BINDING TRANSCRIPTION FACTOR 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the DNA-binding domain of Oct-1 bound to DNA as a dimer
Length: 17
Consensus: CGTTTGAAAGGCAAATG
Weblogo:
PSSM: P0 A C G T
01 0 84 0 12 C
02 14 7 72 3 G
03 0 0 0 96 T
04 5 3 7 81 T
05 3 0 0 93 T
06 0 0 96 0 G
07 81 5 7 3 A
08 96 0 0 0 A
09 96 0 0 0 A
10 3 3 81 9 G
11 12 7 70 7 G
12 0 96 0 0 C
13 96 0 0 0 A
14 96 0 0 0 A
15 96 0 0 0 A
16 1 3 0 92 T
17 7 1 88 0 G
Binding TFs: 1hf0_A / 1hf0_B (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: 1hf0_M
1hf0_N
Publications: Reményi A, Tomilin A, Pohl E, Lins K, Philippsen A, Reinbold R, Schöler H.R, Wilmanns M. Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping. Molecular cell 8:569-80 (2001). [Pubmed]

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