DNA Binding Motif

Accessions: 4aa6_EF (3D-footprint 20231221)
Names: ESTROGEN RECEPTOR
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation
Length: 13
Consensus: AGTCAnnnTGACC
Weblogo:
PSSM: P0 A C G T
01 75 7 7 7 A
02 0 0 96 0 G
03 7 9 7 73 T
04 0 96 0 0 C
05 73 7 7 9 A
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 7 9 7 73 T
10 0 0 96 0 G
11 96 0 0 0 A
12 0 96 0 0 C
13 0 96 0 0 C
Type: Heterodimer
Binding TFs: 4aa6_E (Zinc finger, C4 type (two domains))
4aa6_F (Zinc finger, C4 type (two domains))
Binding Sites: 4aa6_G
4aa6_H
Publications: Schwabe J.W, Chapman L, Rhodes D. The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation. Structure (London, England : 1993) 3:201-13 (1995). [Pubmed]

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