DNA Binding Motif

Accessions: MA0852.1 (JASPAR 2024), PB0018.1 (JASPAR 2024)
Names: Foxk1, Foxk1_1
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: universal protein binding microarray (PBM)
Length: 17
Consensus: wraAtGTAAACAAavrb
Weblogo:
PSSM: P0 A C G T
01 34 19 21 26 w
02 41 12 28 20 r
03 60 7 12 21 a
04 71 4 5 20 A
05 12 12 18 58 t
06 20 1 79 0 G
07 2 0 0 97 T
08 92 8 0 0 A
09 97 1 0 2 A
10 99 0 0 0 A
11 0 89 0 11 C
12 99 0 0 0 A
13 80 6 2 11 A
14 56 9 10 24 a
15 27 30 29 14 v
16 34 22 25 19 r
17 15 27 32 25 b
Type: Heterodimer
Binding TFs: P42128 (Fork head domain, FHA domain)
P42128
Publications: Tsai K.L, Huang C.Y, Chang C.H, Sun Y.J, Chuang W.J, Hsiao C.D. Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins. The Journal of biological chemistry 281:17400-9 (2006). [Pubmed]

Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.