DNA Binding Motif

Accessions: RXRA_full_1 (HumanTF 1.0), MA0512.2 (JASPAR 2024)
Names: RXRA
Organisms: Homo sapiens, Mus musculus
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 14
Consensus: grGGTCAAAGGTCA
Weblogo:
PSSM: P0 A C G T
01 12568 5031 30811 2084 g
02 21345 200 30406 75 r
03 110 77 38290 159 G
04 132 72 36414 4372 G
05 47 109 372 40596 T
06 97 44342 577 2686 C
07 46204 51 120 21 A
08 45275 89 830 368 A
09 45265 73 1369 19 A
10 39 71 39798 51 G
11 63 85 38185 3335 G
12 44 114 267 39867 T
13 63 43686 348 1775 C
14 44403 158 2447 37 A
Type: Heterodimer
Binding TFs: P28700 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains), Nuclear/hormone receptor activator site AF-1)
RXRA_full (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains), Nuclear/hormone receptor activator site AF-1)
P28700
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Zhang X.-K., Lehmann J., Hoffmann B., Dawson M. I., Cameron J., Graupner G., Hermann T., Tran P., Pfahl M. Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature 358:587-591 (1992). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.