DNA Binding Motif

Accessions: 5ego_B (3D-footprint 20231221)
Names: Homeobox protein Hox-B13
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: HOXB13-MEIS1 heterodimer bound to methylated DNA
Length: 7
Consensus: tnnTAaa
Weblogo:
PSSM: P0 A C G T
01 16 16 19 45 t
02 24 24 24 24 n
03 24 24 24 24 n
04 0 0 0 96 T
05 96 0 0 0 A
06 60 12 12 12 a
07 63 10 13 10 a
Binding TFs: 5ego_B (Homeobox domain)
Binding Sites: 5ego_D
5ego_E
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

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