DNA Binding Motif

Accessions: PhoP (DBTBS 1.0)
Names: PhoP
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 18
Consensus: mhTGTwAAgAwrwkwtrW
Weblogo:
PSSM: P0 A C G T
01 12 6 0 4 m
02 8 7 0 7 h
03 0 3 1 18 T
04 4 0 15 3 G
05 0 0 0 22 T
06 9 0 3 10 w
07 20 0 0 2 A
08 17 0 5 0 A
09 5 1 12 4 g
10 15 3 3 1 A
11 11 0 0 11 w
12 8 3 6 5 r
13 6 0 3 13 w
14 2 2 6 12 k
15 8 0 5 9 w
16 3 2 3 14 t
17 13 0 6 3 r
18 15 0 1 6 W
Binding TFs: PhoP (Response regulator receiver domain, Transcriptional regulatory protein, C terminal)
Binding Sites: glpQ_1
phoA_1
phoB_1
phoB_2
phoD_1
phoP_2
phoP_3
phoP_4
phoP_5
pstS_1
resA_1
resD_1
tagA_1
tagA_2
tagA_3
tagD_1
tagD_2
tagD_3
tuaA_1
yfkN
yjdB
ykoL_1
Publications: Antelmann H, Scharf C, Hecker M. Phosphate starvation-inducible proteins of Bacillus subtilis: proteomics and transcriptional analysis. Journal of bacteriology 182:4478-90 (2000). [Pubmed]

Allenby N.E, O'Connor N, Prágai Z, Ward A.C, Wipat A, Harwood C.R. Genome-wide transcriptional analysis of the phosphate starvation stimulon of Bacillus subtilis. Journal of bacteriology 187:8063-80 (2005). [Pubmed]

Liu W, Qi Y, Hulett F.M. Sites internal to the coding regions of phoA and pstS bind PhoP and are required for full promoter activity. Molecular microbiology 28:119-30 (1998). [Pubmed]

Liu W, Hulett F.M. Bacillus subtilis PhoP binds to the phoB tandem promoter exclusively within the phosphate starvation-inducible promoter. Journal of bacteriology 179:6302-10 (1997). [Pubmed]

Abdel-Fattah W.R, Chen Y, Eldakak A, Hulett F.M. Bacillus subtilis phosphorylated PhoP: direct activation of the E(sigma)A- and repression of the E(sigma)E-responsive phoB-PS+V promoters during pho response. Journal of bacteriology 187:5166-78 (2005). [Pubmed]

Eder S, Liu W, Hulett F.M. Mutational analysis of the phoD promoter in Bacillus subtilis: implications for PhoP binding and promoter activation of Pho regulon promoters. Journal of bacteriology 181:2017-25 (1999). [Pubmed]

Paul S, Birkey S, Liu W, Hulett F.M. Autoinduction of Bacillus subtilis phoPR operon transcription results from enhanced transcription from EsigmaA- and EsigmaE-responsive promoters by phosphorylated PhoP. Journal of bacteriology 186:4262-75 (2004). [Pubmed]

Prágai Z, Allenby N.E, O'Connor N, Dubrac S, Rapoport G, Msadek T, Harwood C.R. Transcriptional regulation of the phoPR operon in Bacillus subtilis. Journal of bacteriology 186:1182-90 (2004). [Pubmed]

Qi Y, Kobayashi Y, Hulett F.M. The pst operon of Bacillus subtilis has a phosphate-regulated promoter and is involved in phosphate transport but not in regulation of the pho regulon. Journal of bacteriology 179:2534-9 (1997). [Pubmed]

Birkey S.M, Liu W, Zhang X, Duggan M.F, Hulett F.M. Pho signal transduction network reveals direct transcriptional regulation of one two-component system by another two-component regulator: Bacillus subtilis PhoP directly regulates production of ResD. Molecular microbiology 30:943-53 (1998). [Pubmed]

Liu W, Eder S, Hulett F.M. Analysis of Bacillus subtilis tagAB and tagDEF expression during phosphate starvation identifies a repressor role for PhoP-P. Journal of bacteriology 180:753-8 (1998). [Pubmed]

Robichon D, Arnaud M, Gardan R, Pragai Z, O'Reilly M, Rapoport G, Débarbouillé M. Expression of a new operon from Bacillus subtilis, ykzB-ykoL, under the control of the TnrA and PhoP-phoR global regulators. Journal of bacteriology 182:1226-31 (2000). [Pubmed]

Liu W, Hulett F.M. Comparison of PhoP binding to the tuaA promoter with PhoP binding to other Pho-regulon promoters establishes a Bacillus subtilis Pho core binding site. Microbiology (Reading, England) 144 ( Pt 5):1443-50 (1998). [Pubmed]

Soldo B, Lazarevic V, Pagni M, Karamata D. Teichuronic acid operon of Bacillus subtilis 168. Molecular microbiology 31:795-805 (1999). [Pubmed]

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