DNA Binding Motif

Accessions: 3kmp_AB (3D-footprint 20210203)
Names: SMAD1-MH1
Organisms: Mus musculus
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of SMAD1-MH1/DNA complex
Length: 10
Consensus: TGTCTAGaCT
Weblogo:
PSSM: P0 A C G T
01 3 3 3 87 T
02 0 0 96 0 G
03 3 5 19 69 T
04 2 88 3 3 C
05 0 0 0 96 T
06 96 0 0 0 A
07 3 3 71 19 G
08 63 15 15 3 a
09 0 96 0 0 C
10 3 6 3 84 T
Type: Heterodimer
Binding TFs: 3kmp_A (MH1 domain)
3kmp_B (MH1 domain)
Binding Sites: 3kmp_C
3kmp_D
Publications: BabuRajendran N, Palasingam P, Narasimhan K, Sun W, Prabhakar S, Jauch R, Kolatkar P.R. Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors. Nucleic acids research 38:3477-88 (2010). [Pubmed]

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