DNA Binding Motif

						

			
Accessions: GcvA (RegulonDB 7.5)

			
Names: GcvA, GcvA DNA-binding transcriptional dual regulator
Organisms: ECK12
Libraries: RegulonDB 7.5 1
1 Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muniz-Rascado L, Garcia-Sotelo JS, Weiss V, Solano-Lira H, Martinez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernandez S, Alquicira-Hernandez K, Lopez-Fuentes A, Porron-Sotelo L, Huerta AM, Bonavides-Martinez C, Balderas-Martinez YI, Pannier L, Olvera M, Labastida A, Jimenez-Jacinto V, Vega-Alvarado L, Del Moral-Chavez V, Hernandez-Alvarez A, Morett E, Collado-Vides J. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Res. 2013 Jan 1;41(D1):D203-D213. [Pubmed]
Length: 24
Consensus: hwKvmKSdnWTkWrAwRAwMWAWT
Weblogo: 
PSSM: P0      A      C      G      T
01      2      1      0      1      h
02      2      0      0      2      w
03      0      0      1      3      K
04      2      1      1      0      v
05      2      2      0      0      m
06      0      0      1      3      K
07      0      3      1      0      S
08      2      0      1      1      d
09      1      1      1      1      n
10      3      0      0      1      W
11      0      0      0      4      T
12      0      0      2      2      k
13      3      0      0      1      W
14      2      0      2      0      r
15      4      0      0      0      A
16      2      0      0      2      w
17      3      0      1      0      R
18      4      0      0      0      A
19      2      0      0      2      w
20      1      3      0      0      M
21      1      0      0      3      W
22      4      0      0      0      A
23      3      0      0      1      W
24      0      0      0      4      T
Binding TFs: ECK120006205 (Bacterial regulatory helix-turn-helix protein, lysR family, LysR substrate binding domain)
Binding Sites: ECK120013134
ECK120013136
ECK120013499
ECK120016521
ECK125141478
ECK125141479
			
Publications: Stauffer LT., Stauffer GV. GcvA interacts with both the alpha and sigma subunits of RNA polymerase to activate the Escherichia coli gcvB gene and the gcvTHP operon. FEMS Microbiol Lett. 242(2):333-8 (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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