DNA Binding Motif
| Accessions: | MA0511.1 (JASPAR 2024) |
| Names: | RUNX2 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | ChIP-seq |
| Length: | 15 |
| Consensus: | kkkktyTGTGGTttk |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 99 133 443 387 k 02 165 119 444 334 k 03 151 79 426 406 k 04 121 172 477 292 k 05 124 155 245 538 t 06 75 392 133 462 y 07 9 4 11 1038 T 08 0 1 1030 31 G 09 15 3 0 1044 T 10 0 0 1062 0 G 11 0 0 1060 2 G 12 0 132 90 840 T 13 42 190 158 672 t 14 258 8 143 653 t 15 126 126 462 348 k |
| Type: | Heterodimer |
| Binding TFs: | Q13950 (Runt domain, Runx inhibition domain) Q13950 |
| Binding Sites: | MA0511.1.1 MA0511.1.10 MA0511.1.11 MA0511.1.12 MA0511.1.13 MA0511.1.14 MA0511.1.15 MA0511.1.16 MA0511.1.17 MA0511.1.18 MA0511.1.19 MA0511.1.2 MA0511.1.20 MA0511.1.3 MA0511.1.4 MA0511.1.5 MA0511.1.6 MA0511.1.7 MA0511.1.8 MA0511.1.9 |
| Publications: | van der Deen M, Akech J, Lapointe D, Gupta S, Young D.W, Montecino M.A, Galindo M, Lian J.B, Stein J.L, Stein G.S, van Wijnen A.J. Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility. The Journal of biological chemistry 287:4503-17 (2012). [Pubmed] |
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