DNA Binding Motif

						

			
Accessions: POU3F1_DBD_1 (HumanTF 1.0), MA0786.1 (JASPAR 2024)

			
Names: POU3F1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 2, HT-SELEX
Length: 12
Consensus: wTATGywAATkw
Weblogo: 
PSSM: P0      A      C      G      T
01   1034    126    322   1437      w
02    505    186    128   2471      T
03   2471      7     26     21      A
04     44     53     21   2471      T
05     37     13   2471    232      G
06    170   2471    413   1119      y
07   1423      1     21   1048      w
08   2471    103    130    284      A
09   2471     20     25     63      A
10    259     95    128   2471      T
11    382    302    620   1167      k
12   1510    478    452    961      w
Type: Heterodimer
Binding TFs: POU3F1_DBD (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Q03052 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Q03052
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Verrijzer C. P., Alkema M. J., van Weperen W. W., van Leeuwen H. C., Strating M. J. J., van der Vliet P. C. The DNA binding specificity of the bipartite POU domain and its subdomains. EMBO J. 11:4993-5003 (1992). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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