DNA Binding Motif

						

			
Accessions: IRF9_full (HumanTF 1.0), MA0653.1 (JASPAR 2024)

			
Names: IRF9
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: trimeric; SELEX cycle: 3, HT-SELEX
Length: 15
Consensus: AwCGAAACCGAAACy
Weblogo: 
PSSM: P0      A      C      G      T
01   3467     52     43    110      A
02   2392    498    204   1076      w
03     49   3467     33    118      C
04     43      3   3467      5      G
05   3467      5      1      0      A
06   3467      0      0      3      A
07   3467      2      0      1      A
08     43   3467    197      9      C
09     16   3467      0    831      C
10      2      0   3467      1      G
11   3467      2      0      0      A
12   3467      1      0     21      A
13   3467      0      0      3      A
14      4   3467    239      2      C
15     99   1129      7   2338      y
Type: Heterodimer
Binding TFs: Q00978 (Interferon regulatory factor transcription factor, Interferon-regulatory factor 3)
IRF9_full (Interferon regulatory factor transcription factor, Interferon-regulatory factor 3)
Q00978
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Marquis JF, Kapoustina O, Langlais D, Ruddy R, Dufour CR, Kim BH, MacMicking JD, Giguère V, Gros P. Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. PLoS Genet : (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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