DNA Binding Motif

						

			
Accessions: TFAP2C_DBD_2 (HumanTF 1.0), MA0814.1 (JASPAR 2024)

			
Names: TFAP2C, TFAP2C(var.2)
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 11
Consensus: hGCCtsAGGCw
Weblogo: 
PSSM: P0      A      C      G      T
01   2750   2292    566   2150      h
02    159    836   6921     71      G
03      0   7757    148      0      C
04      3   7757     33    595      C
05    148   1751   1117   4740      t
06   1124   2896   2871    867      s
07   5725    837   1139     56      A
08   1038     85   7757     17      G
09      0    108   7757      0      G
10    127   7064    694     97      C
11   3008    509   1870   2370      w
Type: Heterodimer
Binding TFs: Q92754 (Transcription factor AP-2)
TFAP2C_DBD (Transcription factor AP-2)
Q92754
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Eckert D, Buhl S, Weber S, Jäger R, Schorle H. The AP-2 family of transcription factors. Genome Biol : (2005;6(13):246.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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