DNA Binding Motif

Accessions: 3kov_AB (3D-footprint 2022-04-03)
Names: Myocyte-specific enhancer factor 2A
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of MEF2A bound to DNA reveals a completely folded MADS-box/MEF2 domain that recognizes DNA and recruits transcription co-factors
Length: 10
Consensus: TTAnnnnnAG
Weblogo:
PSSM: P0 A C G T
01 11 9 9 67 T
02 0 0 0 96 T
03 67 9 11 9 A
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 69 9 9 9 A
10 0 0 96 0 G
Binding TFs: 3kov_A / 3kov_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 3kov_C
3kov_D
Publications: Wu Y, Dey R, Han A, Jayathilaka N, Philips M, Ye J, Chen L. Structure of the MADS-box/MEF2 domain of MEF2A bound to DNA and its implication for myocardin recruitment. Journal of molecular biology 397:520-33 (2010). [Pubmed]

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