footprintDB - a database of transcription factors with annotated cis elements (DNA motifs and sites) and binding interfaces

Database 'UniPROBE 20160601' (Transcription Factors 401-450)

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Pages: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14

Accessions	Names	Organisms	Description and notes
UP00609E	CDHS, HuP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, paired box protein PAX3_P50L, WS1, WS3	Homo sapiens	paired box protein Pax-3: This gene is a member of paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent
UP00609F	CDHS, HuP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, paired box protein PAX3_R270C, WS1, WS3	Homo sapiens	paired box protein Pax-3: This gene is a member of paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent
UP00609G	CDHS, HuP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, paired box protein PAX3_R56L, WS1, WS3	Homo sapiens	paired box protein Pax-3: This gene is a member of paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent
UP00609A	CDHS, HuP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, paired box protein PAX3_REF, WS1, WS3	Homo sapiens	paired box protein Pax-3: This gene is a member of paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent
UP00609H	CDHS, HuP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, paired box protein PAX3_Y90H, WS1, WS3	Homo sapiens	paired box protein Pax-3: This gene is a member of paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent
UP00247A	paired box gene 4, Paired box protein Pax-4, Pax4	Mus musculus	paired box gene 4
UP00610B	KPD, MGC129960, MODY9, paired box protein Pax-4, PAX4_R183C	Homo sapiens	paired box protein Pax-4: This gene is a member of paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
UP00610C	KPD, MGC129960, MODY9, paired box protein Pax-4, PAX4_R192H	Homo sapiens	paired box protein Pax-4: This gene is a member of paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
UP00610D	KPD, MGC129960, MODY9, paired box protein Pax-4, PAX4_R192S	Homo sapiens	paired box protein Pax-4: This gene is a member of paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
UP00610A	KPD, MGC129960, MODY9, paired box protein Pax-4, PAX4_REF	Homo sapiens	paired box protein Pax-4: This gene is a member of paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
UP00224A	1500038E17Rik, AEY11, Dey, Dickie's small eye, Gsfaey11, Oculorhombin, paired box 6, Paired box protein Pax-6, Pax6, Sey	Mus musculus Homo sapiens	paired box gene 6
UP00611B	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_A79E, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611C	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_F258S, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611D	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_P118R, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611E	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_P68S, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611F	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_R128C, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611G	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_R242T, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611H	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_R26G, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611A	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_REF, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611I	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_S119R, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00611J	AN, AN2, Aniridia type II protein, D11S812E, MGC17209, MGDA, Oculorhombin, box protein Pax-6, PAX6_V126D, WAGR	Homo sapiens	paired box protein Pax-6: This gene encodes paired box gene one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as anir
UP00248A	paired box gene 7, Paired box protein Pax-7, Pax7	Mus musculus	paired box gene 7
UP00612B	FLJ37460, Hup1, paired box protein Pax-7, PAX7_P112L, PAX7B, RMS2	Homo sapiens	paired box protein Pax-7: This gene is a member of paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma
UP00612A	FLJ37460, Hup1, paired box protein Pax-7, PAX7_REF, PAX7B, RMS2	Homo sapiens	paired box protein Pax-7: This gene is a member of paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma
UP00328A	Hypothetical 59.2 kDa protein in PTC3-SAS3 intergenic region, Pbf1, YBL0509,	Saccharomyces cerevisiae	Myb domain-containing protein YBL054W
UP00280A	Disrupter of telomere silencing protein 6, Pbf2, YER088C	Saccharomyces cerevisiae	Protein of unknown function, involved in telomeric gene silencing and
UP00185A	D230003C07Rik, Homeobox protein PBX1, Pbx-1, Pbx1, pre B-cell leukemia transcription 1, Pre-B-cell leukemia transcription factor 1	Mus musculus	pre B-cell leukemia transcription factor 1
UP00613B	Homeobox protein PBX4, PBX4_R215Q, pre-B-cell leukemia transcription factor 4	Homo sapiens	pre-B-cell leukemia transcription factor 4: This gene encodes a member the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene. [provid
UP00613A	Homeobox protein PBX4, PBX4_REF, pre-B-cell leukemia transcription factor 4	Homo sapiens	pre-B-cell leukemia transcription factor 4: This gene encodes a member the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene. [provid
UP00290A	AMY1, ANT1, BOR2, CYH3, NRA2, Pdr1, Pleiotropic drug resistance protein SMR2, TIL1, TPE1, TPE3, Transcription factor PDR1, YGL013C	Saccharomyces cerevisiae	Zinc cluster protein that is a master regulator involved in other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance ...
UP00463A	AMY2, Pdr3, Pleiotropic Drug Resistance, TPE2	Saccharomyces cerevisiae	Pleiotropic Drug Resistance : Transcriptional activator of the pleiotropic drug network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements); post-translationally up-regulated in cells lacking a functional mitochondrial genome
UP00430A	None, PF07_0126, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00443A	None, PF10_0075_D1, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00443B	None, PF10_0075_D2, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00443C	None, PF10_0075_D3, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00431A	None, PF11_0091, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00432A	None, PF11_0404, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00433A	None, PF11_0442, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00434A	None, PF13_0026, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00435A	None, PF13_0097, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00436A	None, PF13_0235, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00437A	None, PF13_0267, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00438A	None, PF14_0079, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00439A	None, PF14_0533, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00394A	NONE, PF14_0633	Plasmodium falciparum	putative Plasmodium falciparum transcription factor, single AP2 domain
UP00446A	None, PFD0985w_D1, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00446B	None, PFD0985w_D2, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00440A	None, PFE0840c, putative, transcription factor with AP2 domain(s)	Plasmodium falciparum	transcription factor with AP2 domain(s), putative: putative Plasmodium falciparum transcription AP2 domain
UP00393A UP00478B	NONE, PFF0200c, PFF0200c_DLD	Plasmodium falciparum	putative Plasmodium falciparum transcription factor, tandem double AP2 domain
UP00478A	NONE, PFF0200c_D1	Plasmodium falciparum	putative Plasmodium falciparum transcription factor, tandem double AP2 domain

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