19/01/2018 Updated EEADannot
21/12/2017 Updated 3D-foot, interfaces & FASTA files of transcription factors (see download and blog)
03/11/2017 Fixed JASPAR motifs reported in http://jaspar.genereg.net/changelog
23/10/2017 Added JASPAR 2018 collection
13/09/2017 Added humanC2H2ZF-ChIP collection
10/08/2017 Updated HOCOMOCO to v10
28/07/2017 Added HT-SELEX2 with human motifs of TFs bound to methylated and unmethylated ligands
04/05/2017 Added SMILE-seq motifs
22/03/2017 Updated UniPROBE

The data are regularly curated from public databases and the literature; interfaces are inferred from the collection of protein-DNA complexes at 3D-footprint:

total unique metazoa plants
Transcription Factors 8598 6558 4336 1071
DNA motifs (PSSM) 12702 7296 7296 2028
DNA Binding Sites/Sequences 27306

footprintDB predicts:

  1. Transcription factors which bind a specific DNA site or motif
  2. DNA motifs or sites likely to be recognized by a specific DNA-binding protein
footprintDB working schema
footprintDB Search footprintDB Tutorial


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research.