31/05/2022 Updated 3D-footprint & interface residues, synced with RSAT (see blog)
27/05/2022 Added JASPAR 2022 and updated EEADannot
03/03/2022 Updated user manual
23/11/2021 Updated motif & FASTA downloads (see blog)
23/11/2021 Updated EEADannot database, which contains selected plant motifs and sites manually curated at EEAD-CSIC
19/11/2021 Updated server, HTTPS enabled
03/02/2021 Updated 3dfootprint & interfaces
02/12/2020 Curated motifs VRN1, CONS1, CONS2, StCONSTANSlike1 used in doi:10.1016/j.cj.2020.07.008
21/10/2020 Command-line client at GitHub

The data are regularly curated from public databases and the literature; interfaces are inferred from the collection of protein-DNA complexes at 3D-footprint:

total unique metazoa plants
Transcription Factors 9920 7462 4940 1217
DNA motifs (PSSM) 14615 12129 8093 2233
DNA Binding Sites/Sequences 46154

footprintDB predicts:

  1. Transcription factors which bind a specific DNA site or motif
  2. DNA motifs or sites likely to be recognized by a specific DNA-binding protein
footprintDB working schema
footprintDB Search footprintDB Tutorial


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research.