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legend  pdf

structure nameSTRUCTURE OF FOXM1 HOMODIMER BOUND TO A PALINDROMIC DNA SITE
(FORKHEAD BOX PROTEIN M1)
referenceZhang et al. J.Mol.Biol. 434 167426 2021
sourceHOMO SAPIENS
experimentX-ray (resolution=3.10, R-factor=0.221)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
multimeric complexes7fj2_AB 7fj2_EF
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHNSL

Estimated binding specificities ?

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# IC=3.941 IC/col=0.657 n_of_columns=6 specificity:   
A |   0  67  85  52  10  78
C |   0   9   5  16  66   6
G |   0  11   3  14  10   6
T |  96   9   3  14  10   6
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------QTNAST--RGHT--STLA--   L         +-----------------------------2hdc_A    
                                             +-1 
  ----------------RTNT--RGST--NGRT   L     +-2 +-----------------------------2pi0_B    
                                           ! ! 
  ----------TCTG--YTRT------------       +-3 +-----------------------------7vpz_N    
                                         ! ! 
  LAHAKARA------------------------     --4 +-----------------------------6dta_A    
                                         ! 
  --------RC------YC--------------   L   +-----------------------------7cc9_A    
                                       

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updated Fri Dec 23 04:01:40 2022