interface graph thumbnail
legend  pdf

structure nameTHE COMPLEX STRUCTURE OF HSROSR-S1 (VNG0258H/ROSR-S1)
referenceN.KUTNOWSKI et al. NUCLEIC ACIDS RES. V. 47 8860 2019
experimentX-ray (resolution=2.00, R-factor=0.208)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyTranscriptional regulator PadRlike family;
multimeric complexes6qfd_AB 6qh0_AB 6qh0_CD 6qil_AB 6qil_CD 6qua_AB 6qua_CD
redundant complexes6qfd_B 6qh0_A 6qua_C
links to other resourcesPDBSum NPIDB BIPA PDIdb DNAproDB
protein sequence
interface signatureLNHRYPR

Estimated binding specificities ?

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# IC=6.437 IC/col=0.805 n_of_columns=8 specificity:   
A |  11  87   0  96  24   0   8   8
C |   8   1  96   0  24  96  11  69
G |   8   8   0   0  24   0   8  11
T |  69   0   0   0  24   0  69   8
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----LT--NTHG--RT--YTPT----------------RT--   L                               +----------6qil_A    
                                                                     +---------6 
  ------------------NAST--RGHT--STLT----KA--   L                     !         !        +-2c6y_A    
                                                                     !         +--------2 
  --------------------NAST--HT--STLT--------   L                     !                  +-7cby_C    
                                                                  +-10  
  ----------YAQTTC----QC--------------------   L                  !  !                  +-5k5q_D    
                                                                  !  !   +--------------3 
  --------ST--PTTC--STQC------RA------------   L               +-11  +---8              +-1ddn_B    
                                                               !  !      ! 
  ------RAST--ECTT--RAKA--------------HT----   L               !  !      +----------------7oz3_B    
                                                            +-12  !  
  QA--------------------------------------NG                !  !  +-----------------------7k63_U    
                                                            !  !  
  --RC------------------------------------SG                !  !                    +---7cow_T    
                                                            !  +--------------------4 
  ------------------NAST--RTHT--ST----------   L            !                       +---3co7_C    
                                                         +-13  
  --------------------------YG--------------             !  !                         +3eyi_B    
                                                         !  !                   +-----1 
  ----YA--KTPTPG----YTRG--------------------   L         !  !          +--------5     +4mte_D    
                                                         !  !          !        ! 
  --------NT--TCTA--------------------RT----   L      +-14  !      +---7        +-----5zux_A    
                                                      !  !  !      !   ! 
  --------------------RG----YG--------------          !  !  +------9   +--------------1qbj_C    
                                                      !  !         ! 
  --------RG----DTVT----STRG--------WT------   L   +-15  !         +------------------6lxn_A    
                                                   !  !  !  
  ------------------NAST--RGHTNTSTLT--------   L   !  !  +--------------------------7fj2_B    
                                                 -16  !  
  ------------DCKT----RGST--RGYA------------   L   !  +----------------------------4bnc_A    
                                                   !  
  ------------DCKT----RGAT--RCYA------------   L   +----------------------------5e8i_D    
                                                 

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updated Sat Apr 2 01:57:00 2022