| structure name | CRYSTAL STRUCTURE OF A TAILORED I-CREI HOMING ENDONUCLEASE PROTEIN (3115 VARIANT) IN COMPLEX WITH ITS TARGET DNA (HAEMOGLOBIN BETA SUBUNIT GENE) IN THE PRESENCE OF CALCIUM (DNA ENDONUCLEASE I-CREI) |
| reference | Molina et al. 'Sci 8 10286 2018 |
| source | CHLAMYDOMONAS REINHARDTII |
| experiment | X-ray (resolution=2.15, R-factor=0.180) |
| structural superfamily | Homing endonucleases; |
| sequence family | LAGLIDADG endonuclease; |
| multimeric complexes | 6fb0_AB 6fb1_AB 6fb2_AB 6fb5_AB 6fb6_AB |
| redundant complexes | 6fb1_B
6fb2_B
 6fb5_B
6fb6_B
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | SIQKSKKTYSVNYKT |
Estimated binding specificities ?
| readout + contact |  |
A | 71 0 26 56 0 24 0 3 66 C | 3 0 3 3 0 24 96 5 3 G | 19 96 3 14 96 24 0 6 23 T | 3 0 64 23 0 24 0 82 4scan! |
Dendrogram of similar interfaces ?
matrix formatSGIGQAKG----SC--KG----KGTA--YC--ST----VG--YA--KCTG L +6fb0_B +-1 SAIAQGKTNT--SCYAQA----QATCYARG--RG--SAVA------KGTC L +-2 +1t9i_B ! ! STITQAKGRG--STNTQTST--ATTC--YT--SC----VCDTRGSTKGTG L +---3 +3mxb_B ! ! SGIGQAKGNC--SC--RGQG--DGTAYCAT--SC----VCKGRG----TT L +----11 +6fb0_A ! ! STITQANG----ST--RGRG--YCTCYCRG--------VCQT----KGTC L ! ! +3mxb_R ! +--8 SAYCLCITRGDCYA--QG------IG----RG--DT--IC--RG------ L ! +2fld_B ! SGIGQAEC----STYARGKG--KGTA--RT--EC----VG------KTTG L +--------14 +2vbl_A ! ! +-4 SAIAQAKG----ST--RG----QATAYCRT--ST----VA--IT--KTTT L ! ! +-5 +2vbo_A ! ! ! ! SAIAQA------SC--RGKG--QATAYC----ST----VA------KTTT L ! ! +------6 +2vbl_B ! ! ! ! STITQAKGRG--STNTQGST--ATTC--YT--SC----VCDTRGSTKGTG L +-15 +-12 +2xe0_B ! ! ! STMG--------KGYCRT--RGVTSA----MC------STQTRGEC---- L ! ! ! +5esp_A ! ! +-----7 SA--RGRGNT--KTSTSTEC--QGTA----ST------AT--KG------ L ! ! +6bd0_A +---16 ! SAYCKTITRGDCYA----------IG----RG--DT--IC----IA---- L ! ! +-------------------1m5x_B ! ! --MGTASG------RASTRGRGRG--------------DTRGRCEC---- L ! ! +6bce_A ! ! +------10 SGSTLGQG----KTYARGKGVT------HCHG--------QTRTDC---- L +-17 ! ! +4yis_A ! ! +---------13 SCMCRGRG--------YTST--ECTT----RG------TTRG-------- L ! ! ! +5thg_A ! ! +-------9 SC--YT------------RGKGTTTCIG--NA------AT--IC------ L -18 ! +5t8d_A ! ! CA--QGVTRT--DCYA--RT----FA----RGNTDT--MCEA------KA L ! +------------------------5a77_B ! SAIAQAKGNT--SCYAQA----QATGYCRG--RG----VA--------TC L +------------------------1mow_A |
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updated Tue Dec 19 12:48:45 2023