interface graph thumbnail
legend  pdf

structure nameTERNARY COMPLEX OF MTF2, DNA AND HISTONE
(Metal-response element-binding transcription factor 2)
referenceWang et al. Nature 549 287 2017
sourceHomo sapiens
experimentX-ray (resolution=2.25, R-factor=0.204)
structural superfamilyFYVE/PHD zinc finger;Tudor/PWWP/MBT;
sequence familyPHDfinger;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKK

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |   0   0   0  13  13
C |  96  96   0  54  57
G |   0   0  96  13  13
T |   0   0   0  16  13
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----NASTRGHT--ST--   L       +-----------------------------2uzk_A    
                             +-2 
  ECKTRGAT--RGHT----   L     ! !                         +---4mhg_A    
                           +-3 +-------------------------1 
  --KTRG----RGYA----   L   ! !                           +---4l18_B    
                         --4 ! 
  ----NASTRTHT--ST--   L   ! +-----------------------------3l2c_A    
                           ! 
  ----NASTRGHT--STLT   L   +-----------------------------2c6y_A    
                         

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updated Tue Dec 19 11:51:32 2023