interface graph thumbnail
legend  pdf

structure nameBINARY COMPLEX OF PHF1 AND A DOUBLE STRANDED DNA
(PHD finger protein 1)
referenceWang et al. Nature 549 287 2017
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.211)
structural superfamilyFYVE/PHD zinc finger;Tudor/PWWP/MBT;
sequence familyPHDfinger;
redundant complexes5xfq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKK

Estimated binding specificities ?

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# IC=2.759 IC/col=0.552 n_of_columns=5 specificity:   
A |   9   5   3   8  12
C |  82  81  21  71  41
G |   4   6  68   8  23
T |   1   4   4   9  20
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----NASTRTHT--ST----   L       +-----------------------------3l2c_A    
                               +-1 
  ----NASTRGHT--ST----   L   +-2 +-----------------------------2uzk_A    
                             ! ! 
  ----NASTRGHT--STLT--   L --3 +-----------------------------2c6y_A    
                             ! 
  ECKTRGAT--RGHT----RA   L   +-----------------------------4mhg_A    
                           

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updated Tue Dec 19 11:51:08 2023