interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of 'DNA polymerase beta, N-terminal domain-like', as these often contain single-stranded DNA molecules which accumulate many base contacts which distort the calculations.


Dendrogram of similar interfaces ?

matrix format
structure namePOST-CATALYTIC COMPLEX OF HUMAN POLYMERASE MU (W434H) MUTANT WITH INCOMING DTTP
(DNA-directed DNARNA polymerase mu)
referencePedersen et al. 'Nucleic 45 9138 2017
sourceHomo sapiens
experimentX-ray (resolution=1.50, R-factor=0.172)
structural superfamilyNucleotidyltransferase;DNA polymerase beta, N-terminal domain-like;PsbU/PolX domain-like;
sequence familyFingers domain of DNA polymerase lamb;
redundant complexes4m0a_A 5twq_A 5tws_A 5tye_A 5tyf_A 5tyg_A 5tyx_A 5tyy_A 5tyz_A 5vz9_A 5vzc_A 5vzf_A 6p1s_A 6p1u_A 6wie_A 7ksu_A 7ksv_A 7ksx_A 7ksy_A 7kt2_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  ----LC--RCRAFT--KTQTRARA                                 +5vzi_A    
                                            +--------------1 
  --SALTAART------RGEGRGRG             +----3              +4qz9_A    
                                       !    ! 
  --SALTAART------RGEGRGRG          +--4    +--------------6go6_A    
                                    !  ! 
  HC--------KG--YCDCNCKGRG       +--5  +-------------------4kli_A    
                                 !  ! 
  WC--LC----KA--YCAGNGRCRG     --6  +----------------------2bcq_A    
                                 ! 
  ----------KC----KA--VARA       !            +------------4p4m_A    
                                 +------------2 
  ----------KT--HCVGLCIGRG                    +------------5hrb_A

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updated Tue Dec 19 11:33:43 2023