| structure name | CRYSTAL STRUCTURE OF CTCF(ZNF 4-10) WITH 28-MER DNA (Transcriptional repressor CTCF) |
| reference | Horton et al. 'Mol. 66 711 2017 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.55, R-factor=0.212) |
| structural superfamily | beta-beta-alpha zinc fingers; |
| sequence family | Zinc finger, C2H2 type; |
| multimeric complexes | 5und_AB |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | EKRKRQTSDV |
Estimated binding specificities ?
| readout + contact |  |
A | 8 0 0 0 0 0 0 0 9 11 0 0 8 C | 69 0 96 96 96 96 96 0 0 69 0 0 19 G | 8 96 0 0 0 0 0 0 87 8 0 96 61 T | 11 0 0 0 0 0 0 96 0 8 96 0 8scan! |
Dendrogram of similar interfaces ?
matrix format--ECSCKGRG--DCTCYCKGRG----QA----TC------RC--SCDC--VT L +-----5und_A +-4 --ECSCKGRG----TCYCKARG--TCQAST--TC------RC--SCDC--VT L +-5 +-----5yef_B ! ! ------------DC--YCKGRG----QA----TC------RC--SCDC--VT L +-----------6 +-------5k5i_A ! ! --ECSGKGRG--DG--YCKGRG----QA----TC------RA--SCDC--VT L ! +--------5k5h_A +--9 FT--KAYT----WT--WTSTET----FTVASGDCSARG-------------- L ! ! +---6jnm_A ! ! +------------3 NGKTWTKG--------HTHGRG--TGTT--ACNA--KGRG------------ L ! +---7 +---1tf3_A +-10 ! ------------------YG------WT--WTST--ET--FTVASGDCSART L ! ! +----------------6a57_A ! ! ----------RGST--YGYC------QC--TGSTRAYT-------------- L ! ! +3uk3_C +-11 +-----------------------1 ------------NT--STNAVT----QTSTSGKG--RG-------------- L ! ! +6u9q_A ! ! --TTTCLA----TTSC--ECRGYG--EC--SCKG--RG--DG--YCKG--RG L ! ! +--5t0u_A +-12 ! +--------------2 ----SGHGRGRGDC--SCHG------DC--SANA------WC--SCVG--RG L ! ! +------8 +--5v3g_A ! ! ! ------------DC--SCQGKT--TTAT--SCSC------DC--SGATRARG L -13 ! +-----------------6ml4_A ! ! ----TCSGRG--LT--ETYC------NTYGQG-------------------- L ! +---------------------------6dfb_A ! ----------------------------------------RG--SGDC---- L +----------------------------5k5l_F |
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updated Tue Dec 19 11:25:29 2023