5nm9_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE PLACOZOA TRICHOPLAX ADHAERENS SMAD4-MH1 BOUND TO THE GGCGC SITE. (Mothers against decapentaplegic homolog)
reference	Kaczmarska et al. 'Nat 8 2070 2017
source	Trichoplax adhaerens
experiment	X-ray (resolution=2.43, R-factor=0.222)
structural superfamily	SMAD MH1 domain;
sequence family	MH1 domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5nm9_A interface=67,69,74, atlgivhtlmchrqggesenfakraveslvkklkdkrdeldalitavtsngiqqskcvtiartldgRlQvagkKgfphviysriwrwpdlhknelkhiklckfafdlkldhvcvnpyhyerv
interface signature	RQK

Estimated binding specificities ?

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# IC=4.981 IC/col=0.830 n_of_columns=6

specificity:

A |  16   0  24   0   0   8
C |   8   0   8  96   0  72
G |  56  96  48   0  96   8
T |  16   0  16   0   0   8

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Dendrogram of similar interfaces ?

matrix format

  
  DCRGQC--KG   L            +6tbz_A    
                          +-2 
  --RGQC--KG   L   +------4 +5od6_A    
                   !      ! 
  --RGQA--KA   L   !      +-6h3r_A    
                 --6 
  DCRGQC--KG   L   !      +-6fzt_A    
                   +------5 
  --RGQA--KG   L          ! +3kmp_A    
                          +-3 
  DCRGQC--KG   L            ! +6zmn_B    
                            +-1 
  --RGQAHTKG   L              +5x6g_A

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updated Tue Dec 19 10:57:25 2023