5nfv_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE FNCAS12 MUTANT BOUND TO AN R-LOOP STRUCTURE CONTAINING A PRE-CRRNA MIMIC AND FULL-LENGTH DNA TARGET (CRISPR-associated endonuclease Cpf1)
reference	van der Oost et al. 'Mol. 66 221 2017
source	Francisella tularensis subsp. novicida (strain U112) / Francisella tularensis subsp. novicida (strain U112)
experiment	X-ray (resolution=2.50, R-factor=0.207)
redundant complexes	6gtd 6gtg 5mga 6i1k 6i1l 6gtc 6gte 6gtf
reference complex	6gtc_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5nfv_A interface=175,183,287,449,561,562,582,591,594,641,644,645,646,649,729,732,733,805,861,872,1124, nasiyqefvnkyslsktlrfelipqgktlenikarglilddekrakdykkakqiidkyhqffieeilssvcisedllqnysdvyfklkksdddnlqkdfksakdtikkqiseyikdsekfknlfnqnlidakksdlilwlkqskdngielfkansditdidealeiiksfkgwtTyfkgfheNrknvyssndiptsiiyrivddnlpkflenkakyeslkdkapeainyeqikkdlaeeltfdidyktsevnqrvfsldevfeianfnnylnqsgitkfntiiggkFvngentkrkgineyinlysqqindktlkkykmsvlfkqilsdtesksfvidkleddsdvvttmqsfyeqiaafktveeksiketlsllfddlkaqkldlskiyfkndksltdlsqqvfddysvigtavleyitqktekakylsletiklaleefnkhrdidKqcrfeeilanfaaipmifdeiaqnkdnlaqisikyqnqgkkdllqasaeddvkaikdlldqtnnllhklkifhisqsedkanildkdehfylvfeecyfelanivplynkiRNyitqkpysdekfklnfensTlangwdknKepDntailfikddkyylgvmnkknnkifddkaikenkgegykkivykllPgaNKMlpKvffsaksikfynpsedilrirnhsthtkngspqkgyekfefniedcrkfidfykqsiskhpewkdfgfrfsdtqrynsiDefYRevenqgykltfenisesyidsvvnqgklylfqiynkdfsayskgrpnlhtlywkalfdernlqdvvyklngEaelfyrkqsipkkithpakeaianknkdnpkkesvfeydlikdkrftedkfffhcPitinfkssgaNkfndeinlllkekandvhilsidrgerhlayytlvdgkgniikqdtfniigndrmktnyhdklaaiekdrdsarkdwkkinnikemkegylsqvvheiaklvieynaivvfqdlkvekqvyqklekmlieklnylvfkdnefdktggvlrayqltapfetfkkmgkqtgiiyyvpagftskicpvtgfvnqlypkyesvsksqeffskfdkicynldkgyfefsfdyknfgdkaakgkwtiasfgsrlinfRndtrevyptkelekllkdysieyghgecikaaicgesdkkffakltsvlntilqmansktdylispvadvngnffdsrqapknmpqdadangayhiglkglmllgriknnqegkklnlvikneeyfefvqnrnn
interface signature	TNFKRNTKDPNKMKDYREPNR

Estimated binding specificities ?

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# IC=5.116 IC/col=0.320 n_of_columns=16

specificity:

A |  12   4   4  96  12   0  14  31  31  24  24  24  24  27  24  20
C |  12   4   7   0  12  96  14  23  21  24  24  24  24  22  24  19
G |  12   7   4   0  12   0  14  21  21  24  24  24  24  25  24  19
T |  60  81  81   0  60   0  54  21  23  24  24  24  24  22  24  38

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updated Mon Dec 18 13:22:54 2023