interface graph thumbnail
legend  pdf

structure nameWILMS TUMOR PROTEIN (WT1) Q369R ZNF2-4 IN COMPLEX WITH DNA
(Wilms tumor protein)
referenceHashimoto et al. 'Nucleic 44 10165 2016
sourceHomo sapiens
experimentX-ray (resolution=1.64, R-factor=0.175)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex5kl3_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDRRRDHTRDER

Estimated binding specificities ?

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# IC=11.267 IC/col=1.127 n_of_columns=10 specificity:   
A |   0   0   0   0   0   0   0   0   0  16
C |   0  80   0   0   0   0   0   0   0  16
G |  96   0  96  16  96  96  96  96  96  48
T |   0  16   0  80   0   0   0   0   0  16
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updated Mon Dec 18 13:13:34 2023