interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF REP-DNA COMPLEX
(Replication initiator A, N-terminal)
reference'Proc. 111 9121 2014 X-RAY DIFFRACTION
sourceStaphylococcus aureus
experimentX-ray (resolution=3.09, R-factor=0.231)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyReplication initiator protein A RepA Nter;
multimeric complexes5kbj_ABG
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERLN

Estimated binding specificities ?

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# IC=8.621 IC/col=0.862 n_of_columns=10 specificity:   
A |   0  96  50   1   5  24   5   0   6  16
C |   0   0  20  90   5  24  81   0   5   0
G |  96   0  10   5   0  24   5   0  80  80
T |   0   0  16   0  86  24   5  96   5   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------RGYG--           +-----------------------------1qbj_C    
                             +-1 
  QTSTRTETTA--RA----   L   +-2 +-----------------------------3iyd_H    
                           ! ! 
  --TT--SGLTYA------   L --3 +-----------------------------2nra_C    
                           ! 
  ------TTHT--KG--RC   L   +-----------------------------7b0c_A    
                         

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updated Tue Dec 19 10:49:29 2023