interface graph thumbnail
legend  pdf

structure nameHOMO SAPIENS CCCTC-BINDING FACTOR (CTCF) ZNF6-8 AND H19 SEQUENCE DNA COMPLEX STRUCTURE
(Transcriptional repressor CTCF)
referenceHashimoto et al. 'Mol. 66 711 2017
sourceHomo sapiens
experimentX-ray (resolution=3.13, R-factor=0.238)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSD

Estimated binding specificities ?

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# IC=2.288 IC/col=0.572 n_of_columns=4 specificity:   
A |  10   8   0  19
C |  10  72   0  19
G |  63   8  96  39
T |  13   8   0  19
scan!

Dendrogram of similar interfaces ?

matrix format



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updated Tue Dec 19 10:48:36 2023