interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE BACTERIOHAGE T5 D15 FLAP ENDONUCLEASE (D155K) PSEUDO-ENZYME-PRODUCT COMPLEX WITH DNA AND METAL IONS
(EXODEOXYRIBONUCLEASE)
referenceSedelnikova et al. Nat.Struct.Mol.Biol. 23 640 2016
sourceESCHERICHIA PHAGE T5
experimentX-ray (resolution=1.86, R-factor=0.160)
structural superfamilyPIN domain-like;5' to 3' exonuclease, C-terminal subdomain;
multimeric complexes5hnk_AB
redundant complexes5hnk_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureFRKHNNSLYKTEELFFTRL

Estimated binding specificities ?

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# IC=5.463 IC/col=0.607 n_of_columns=9 specificity:   
A |  33  24  24  24   0  21   0  96   0
C |  21  24  24  24   0  42  96   0   0
G |  21  24  24  24  96  23   0   0   0
T |  21  24  24  24   0  10   0   0  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------FCRT--KCHANGNASA----LT------KCTGEGEGLGFTFC----RTLA   L               +------5hp4_A    
                                                                          +--1 
  ------------------------------------------------------SG       +--------2  +------3zdb_A    
                                                                 !        ! 
  IGSTTGLTVA------------NCKAKANAKASA--------------MAHT----     --3        +---------2ihn_A    
                                                                 ! 
  ----------AG--------------------------------------------       +------------------5k97_A    
                                                               

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updated Tue Dec 19 10:32:59 2023