interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYSTAL STRUCTURE OF NUCLEOSOME COMPLEX WITH HUMAN TESTIS-SPECIFIC HISTONE VARIANTS, TH2A
(HISTONE H2A TYPE 1-A)
referenceKumarevel et al. 'Biophys. 221 41 2017
sourceHOMO SAPIENS
experimentX-ray (resolution=2.82, R-factor=0.214)
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes5gsu_ABCDEFGH 5gt0_ABCDEFGH
redundant complexes5gsu_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  --------RART                                 +3x1t_G    
                                             +-1 
  --------RG--                               ! +6k1k_C    
                                             !  
  --------RC--                            +-16    +6qld_g    
                                          !  !  +-3 
  --------RG--                            !  !  ! +4jjn_G    
                                          !  +-14  
  --------RT--                            !     !  +6px1_C    
                                          !     +-11  
  ------RART--                            !        +4x23_Q    
                                       +-19  
  --------RT--   L                     !  !         +2f8n_G    
                                       !  !       +-2 
  --------RA--                         !  !     +-9 +1kx5_G    
                                       !  !     ! ! 
  --------RT--                         !  !  +-13 +5gt0_C    
                                       !  !  !  !  
  --------RT--                      +-20  !  !  ! +2f8n_K    
                                    !  !  +-15  +-4 
  --------RA--                      !  !     !    +6t79_C    
                                    !  !     !  
  --------RT--                      !  !     !  +5z23_C    
                               +---21  !     +-10  
  --------RT--                 !    !  !        +6jou_C    
                               !    !  !  
  --------RT--             +--23    !  +---6m4g_G    
                           !   !    !  
  --------RT--             !   !    +-----6m4d_C    
                           !   !  
  --AT--------          +-25   +----------6r2v_C    
                        !  !  
  RAETRT------          !  !               +4ne1_p    
                        !  !             +-8 
  --LT--------       +-26  +------------17 +6mup_E    
                     !  !                !  
  --------RG--       !  !                +5t5k_E    
                     !  !  
  --IT--------       !  +----------------3wkj_D    
                     !  
  --------RC--       !                     +6qld_f    
                   -27                   +-5 
  --------RC--       !                 +-6 +6uph_B    
                     !                 ! ! 
  --------RT--       !       +--------12 +6ipu_B    
                     !       !         !  
  --------RC--       !    +-22         +4jjn_B    
                     !    !  !  
  --IT--------       !    !  +---------6ipu_H    
                     +---24  
  --LC----RG--            !           +4jjn_A    
                          !         +-7 
  --LT----RC--            +--------18 +6ipu_E    
                                    !  
  --LT--------                      +-6e0p_A    
                   

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updated Tue Dec 19 10:27:06 2023