5dwa_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF PRE-SPECIFIC RESTRICTION ENDONUCLEASE AGEI-DNA COMPLEX (Type-2 restriction enzyme AgeI)
reference	Tamulaitiene et al. 'Nucleic 45 3547 2017
source	Thalassobius gelatinovorus
experiment	X-ray (resolution=1.50, R-factor=0.155)
multimeric complexes	5dwa_AB 5dwb_AB
redundant complexes	5dwb_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5dwa_A interface=86,89,90,120,172,173,174,200,202,203,206,214,224, mrldldfgrglvahvmldnvseeqyqqisdyfvplvnkpklksrdaigqafvmatevcpdanpsdlwhhvlyriyirekigtdpsQswVRtsgeafevalverynpvlarhgirltalfKgqkglaltrmgvadrvgsrkvdvmiekqgggrspdaegfgvvggihakvslAERvsddipasrimmgegllsvlstldvKsFPppHgdlvnrgElgtpdrpsdKrnyieghgdfsacfsynlrtspsnattpsgrhiyvsgfsgqddeftdylvaqla
interface signature	QVRKAERKFPHEK

Estimated binding specificities ?

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# IC=10.397 IC/col=1.040 n_of_columns=10

specificity:

A |   8   0  72   0   0   0   8   0   0   0
C |  72   0   8  96  96   0   8   0  88   8
G |   8  96   8   0   0  96  72   0   8  88
T |   8   0   8   0   0   0   8  96   0   0

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: AGEI
CCGGT	PubMed	5dwa_A(5.83e-06), 5dwa_AB(6.30e-06), 5dwb_AB(1.10e-05), ... (total=4)

Dendrogram of similar interfaces ?

matrix format

  
  ----------QG--VCRC--KG--AAEARG--KTFCPTHC--   L             +-------------------5dwa_A    
                                                       +-----1 
  ------------QG--ACKG--RGKGECVC----------RT   L     +-2     +-------------------6eko_A    
                                                     ! ! 
  ------------------------RGSGDCRG----------   L   +-3 +-------------------------1fiu_B    
                                                   ! ! 
  --NCSTNARG--------------------------------   L --4 +--------------------------1mnm_C    
                                                   ! 
  RTVAQTNA----------------------------------   L   +---------------------------5hod_A

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updated Tue Dec 19 10:16:44 2023