interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HINMLR, A MERR FAMILY REGULATOR LACKING THE SENSOR DOMAIN, BOUND TO PROMOTER DNA
(MerR family regulator protein)
referenceCounago et al. 'Nucleic 44 6981 2016
sourceHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) / Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
experimentX-ray (resolution=2.25, R-factor=0.209)
structural superfamilyPutative DNA-binding domain;
sequence familyMerR family regulatory protein;
multimeric complexes5d8c_AB 5e01_AB
redundant complexes5e01_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYRFK

Estimated binding specificities ?

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# IC=3.968 IC/col=0.661 n_of_columns=6 specificity:   
A |   9  24  67   0  67   0
C |  11  24   9   0   9   0
G |   9  24   9  96  11  96
T |  67  24  11   0   9   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  YTRTFCKG--   L             +--------5d8c_A    
                     +-------3 
  EARTYARTYG   L     !       !  +-----6jgx_B    
                     !       +--2 
  RGHTHC--YG   L   +-4          +-----1r8d_B    
                   ! ! 
  RGRTYT--KT   L   ! !               +7tea_B    
                 --5 +---------------1 
  RCRT------       !                 +7tec_A    
                   ! 
  RART------       +------------------4r24_B    
                 

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updated Tue Dec 19 10:13:54 2023