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structure nameSTRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE BOUND TO A NOVEL 38-MER HAIRPIN TEMPLATE-PRIMER DNA APTAMER
referenceMiller et al. 'Protein 25 46 2016
experimentX-ray (resolution=2.30, R-factor=0.191)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyReverse transcriptase connection domain; Reverse transcriptase RNAdependent DNA; RNase H; Reverse transcriptase thumb domain;
multimeric complexes1hys_AB 1j5o_AB 1n5y_AB 1n6q_AB 1r0a_AB 1rtd_AB 1rtd_CD 1t03_AB 1t05_AB 2hmi_AB 3jsm_AB 3jyt_AB 3kjv_AB 3kk1_AB 3kk2_AB 3kk3_AB 3kle_AB 3kle_EF 3kle_MN 3klf_AB 3klf_EF 3klf_MN 3klg_AB 3klg_EF 3klh_AB 3v4i_AB 3v4i_CD 3v6d_AB 3v6d_CD 3v81_AB 3v81_CD 4b3o_AB 4b3p_AB 4b3q_AB 4pqu_AB 4pqu_CD 4puo_AB 4puo_CD 4pwd_AB 4pwd_CD 4q0b_AB 4q0b_CD 4r5p_AB 4r5p_CD 5d3g_AB 5d3g_CD 5hlf_AB 5hlf_CD 5hp1_AB 5hp1_CD 5hro_AB 5hro_CD 5i3u_AB 5i3u_CD 5i42_AB 5i42_CD 5j2m_AB 5j2n_AB 5j2p_AB 5j2q_AB 5txl_AB 5txl_CD 5txm_AB 5txm_CD 5txn_AB 5txn_CD 5txo_AB 5txo_CD 5txp_AB 5txp_CD 5xn0_AB 5xn0_CD 5xn1_AB 5xn1_CD 5xn2_AB 5xn2_CD 6amo_AB 6amo_CD 6an2_AB 6an2_CD 6an8_AB 6an8_CD 6anq_AB 6anq_CD 6asw_AB 6asw_CD 6avm_AB 6avm_CD 6avt_AB 6avt_CD 6bsg_AB 6bsh_AB 6bsi_AB 6bsj_AB 6ik9_AB 6ik9_CD 6ika_AB 6ika_CD 6kdj_AB 6kdj_CD 6kdk_AB 6kdk_CD 6kdm_AB 6kdm_CD 6kdn_AB 6kdn_CD 6kdo_AB 6kdo_CD 6o9e_AB 6o9e_CD 6or7_AB 6otz_AB 6oun_AB 6p1i_AB 6p1x_AB 6p2g_AB 6uir_AB 6uis_AB 6uit_AB 6ujx_AB 6ujy_AB 6ujz_AB 6uk0_AB 6vug_AB 6wpf_AB 6wph_AB 6wpj_AB 7ahx_AB 7ahx_CD 7aid_AB 7aid_CD 7aif_AB 7aif_CD 7aig_AB 7aig_CD 7aii_AB 7aii_CD 7aij_AB 7aij_CD 7dbm_AB 7dbm_CD 7dbn_AB 7dbn_CD 7lri_AB 7lri_CD 7lrm_AB 7lrm_CD 7lrx_AB 7lrx_CD 7lry_AB 7lry_CD 7lsk_AB 7lsk_CD 7ot6_AB 7ot6_CD 7ota_AB 7ota_CD 7otk_AB 7otk_CD 7otn_AB 7otn_CD 7otx_AB 7otx_CD 7otz_AB 7otz_CD 7out_AB 7out_CD 7oxq_AB 7oxq_CD 7oz2_AB 7oz2_CD 7oz5_AB 7oz5_CD 7ozw_AB 7p15_AB 7z24_AB 7z29_AB 7z2d_AB 7z2e_AB 7z2g_AB 7z2h_AB
redundant complexes6uir 1n5y 6kdo 6uis 6uit 6bsg 6ujx 6wpf 6bsh 6ujy 6wph 6bsi 6ujz 6wpj 6bsj 6uk0 1n6q 3jyt 5i3u 4q0b 6kdj 5txl 6p1i 6p1x 6p2g 6kdk 4pwd 1r0a 4b3q 4puo 6amo 7oxq 6an2 1rtd 6an8 7lri 5hro 6anq 3kjv 7lrm 6kdm 3kk1 7lrx 4b3o 1j5o 6kdn 3kk2 7lry 4b3p 3kk3 7lsk 5txp 2hmi 4r5p 7oz2 5hp1 3v4i 7oz5 7ozw 3kle 7p15 5xn1 3klf 6vug 3klg 3klh 6asw 5hlf 5i42 6avm 1hys 1t03 1t05 6o9e 3v6d 7ot6 6ik9 7ota 6ika 7otk 3jsm 7otn 6avt 7otx 4pqu 7otz 7out 5xn0 5txn 7dbm 3v81 6or7 7dbn 7ahx 7aid 6otz 7aif 6oun 7aig 7aii 7aij 5txo 5j2m 5j2n 5j2p 5xn2 5j2q 5txm
reference complex7ozw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  WTFARALADTRT--ICYGQAPCYGMGNC----RT------------QGYT--   L                       +---------5d3g_A    
                                                                     +-----------1 
  --------------------PGYT----------------------------               !           +---------4hkq_A    
                                                               +-----3 
  YC------DGRT----------------------------------------         !     !       +-------------6mih_A    
                                                             +-4     +-------2 
  ------------FC--------YA----------------------------       ! !             +-------------6ar1_A    
                                                           --5 ! 
  ------------------------------NT------------NGNG--LT       ! +---------------------------4h8k_A    
                                                             ! 
  ----------------------------RGRG--WAECRGRGWC--------   L   +----------------------------1gcc_A

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updated Thu Dec 22 03:26:28 2022