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structure nameCRYSTAL STRUCTURE OF LAGLIDADG MEGANUCLEASE I-GPEMI BOUND TO UNCLEAVED DNA
(Ribosomal protein 3homing endonuclease-like fusion protein)
referenceHallinan et al. Structure 24 862 2016
sourceGrosmannia penicillata
experimentX-ray (resolution=2.15, R-factor=0.181)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSRRNKSSEQTSASKCFSISSQQTYKKKFWET

Estimated binding specificities ?

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# IC=21.426 IC/col=0.974 n_of_columns=22 specificity:   
A |   7  15  24   8   0   0   0   0   0  19  96  24   0   0  96  61   0   0   0   0   0   0
C |  17  13  24   5  96  96   1  96  89   7   0  24   0  96   0  35  96  96  95   0   0   0
G |   7  17  24   1   0   0  65   0   0  15   0  24   0   0   0   0   0   0   0   0   0   0
T |  65  51  24  82   0   0  30   0   7  55   0  24  96   0   0   0   0   0   1  96  96  96
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Dendrogram of similar interfaces ?

matrix format

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updated Tue Dec 19 09:46:56 2023