| structure name | CRYSTAL STRUCTURE OF THE ETS DOMAIN OF HUMAN ETV5 IN COMPLEX WITH DNA (ETS TRANSLOCATION VARIANT 5) |
| reference | Burgess-Brown et al. J.Biol.Chem. 290 13692 2015 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=1.95, R-factor=0.175) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Etsdomain; |
| multimeric complexes | 4uuv_AM 4uuv_DP 4uuv_GJ 4uuv_SV |
| redundant complexes | 4bnc_A
 4uuv_D
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | DKRSRY |
Estimated binding specificities ?
| readout + contact |  |
A | 0 0 0 60 24 60 C | 84 0 0 12 24 12 G | 0 96 96 12 24 12 T | 12 0 0 12 24 12scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: ETV5 | ||
| CGGAAGTGACGTCA | PubMed | 4uno_A(1.19e-02) |
| CCGGAAGCGGAA | PubMed | 4uno_A(8.48e-03) |
Dendrogram of similar interfaces ?
matrix format--------------KT--RG--RGYA------ L +-----------------------------3wts_C +-1 ------------------TT--CT--NGKG-- L +-2 +-----------------------------7oot_B ! ! ------------------TT--CT--NGKG-- L +-3 +-----------------------------7rh2_B ! ! --LT----NTHGTA--YTRG------------ +-4 +-----------------------------2efw_A ! ! --------------------NTCT--NGST-- L +-5 +-----------------------------1if1_B ! ! ----RC-------------------------- +-6 +-----------------------------7cow_T ! ! RC------------------------------ --7 +-----------------------------6l9z_S ! ------LTNTHG--RTYTPT----------RT L +-----------------------------6qil_A |
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updated Tue Dec 19 09:31:56 2023